After several months, they put their plan into practice, kidnapping the man and spiriting him away to a flat in the city. They gain access to his home by taking the jobs of a maid and a chauffeur. He and Jeanne hatch a plan to kidnap and hold a French-Canadian billionaire, a decrepit man paralyzed from the waist down. Mesrine is denied residency in Canada due to his criminal past but he remains there illegally. Later, in Montreal, he works as a construction worker on the Champlain Bridge, where he meets a Quebec resident, Jean-Paul Mercier, and they become friends. He packs, leaves his kids in custody of his parents, and departs from France, traveling to Canada with Jeanne.
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Guido treats him for his injuries, and suggests that he should leave the country until the things cool down, to which Mesrine agrees. In 1968, while walking with his young daughter, several men pull a 'drive-by' on Mesrine, wounding him. After stealing from a mob operated casino, the pair attract the attention of local mob bosses. Jeanne is cut from the same cloth as Mesrine and the pair begin to commit robberies together. A woman named Jeanne Schneider comes on to him and the pair quickly fall in love. In 1966, Mesrine, now a gangster, goes into a bar. Later they divorce, leaving him custody of the children. One night, Guido and Paul arrive and Mesrine prepares to leave with them, but Sofia yells at him and tells him that she will call the police, on which Mesrine snaps, slaps her, drags her across the stairs, and shoves a gun into her mouth and threatens her in front of Guido and Paul before departing. He is released in 1962, and although tries to keep a steady job and be honest, he is fired during an economic downturn, and dreams of easy money get him back into 'the business'. However, although they have a daughter, and later two sons, Mesrine continues to be in the robbery business, causing him to get arrested and sent to prison in late 1960. Using Guido's status as a local crime boss as protection from their enemies, after committing some robberies, Paul and Mesrine briefly leave France for the Canary Islands, where Mesrine meets and falls in love with Sofia, who moves to France with him, and they marry. Later, Guido and Mesrine kill Ahmed, an Arab pimp who beat up Sarah (one of his girls and Mesrine's girlfriend), and bury him in the countryside and drive off. They soon get into robbery business with Paul's boss, Guido, and from him, he obtains a Citroën DS as a loan. After an argument about getting an honest job, he meets with his old childhood friend, Paul, who is wealthy now and drives a sports car.
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On his return to France, he moves into his parents' home, where he reunites with his mother and his father. Part 1 depicts Mesrine's life from 1959 to 1972, beginning with his time as a member of the French Army during the Algerian War, where he was forced to shoot and kill prisoners and bomb-makers.
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1") known in English as Public Enemy Number One (Part Two), Mesrine: Part 2 - Public Enemy #1 and Mesrine: Public Enemy Number One Mesrine: L'ennemi public No 1 ( French for "Mesrine: Public Enemy No.Mesrine: L'instinct de mort ( French for "Mesrine: Instinct for Death") known in English as Public Enemy Number One (Part One), Mesrine: Part 1 - Death Instinct and Mesrine: Killer Instinct.The film is divided into two parts, with various titles: